Candida auris cases reported in Buenos Aires

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On October 28, the National Institute of Infectious Diseases (INEI) of the National Administration of Laboratories and Institutes of Health (ANLIS) announced that “Dr. Carlos G. Malbrán” reported to the Directorate of Epidemiology of the National Ministry of Health two isolates of Candida auris from clinical samples of two treated patients. In a clinic in the autonomous city of Buenos Aires. They were identified in a special laboratory in the city by MALDI-TOF technology and referred to the INEI National Reference Laboratory for Clinical Mycology (LNRM) on the same day.

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Under this situation, the Executive Department of Epidemiology of the Ministry of Health of the Autonomous City of Buenos Aires was informed and a joint meeting was held between the authorities, workers of the private enterprise and technical teams from the city and the Ministry of Health of a nation.

At the same time, the INEI LNRM received samples from the laboratory that made the first diagnosis and confirmed the identification of Candida auris also by MALDI-TOF. It also conducted antifungal sensitivity studies, the results of which appeared on October 31, and advised responsible personnel to be able to provide appropriate treatment.

One of the isolates comes from a patient who has been hospitalized since October 2 in the intensive care unit of the CABA Clinic. He was referred from an overseas clinic, taken on a medical flight and is currently in hospital. On October 18, a urine culture was performed to isolate Candida sp. , which was identified on October 28 as Candida auris by MALDI-TOF technology in a special laboratory.

The other isolation corresponds to a patient being treated on an outpatient basis in the same clinic. On October 13, this patient underwent a peritoneal fluid transplant in which a yeast also identified as Candida auris was isolated on October 28.

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The patients did not share the same environment at the same time during their stay in the clinic and epidemiological investigation is ongoing.

Based on the information available to date, the nation’s Ministry of Health teams (National Institute of Infectious Diseases Department of Mycology, NIHD’s Program of Epidemiology and Infection Control “VIHDA”, Appropriate Coordination of Antimicrobial Use, and Department of Epidemiology) and Department The Operational Epidemiology Department of the Ministry of Health of the City of Buenos Aires made recommendations for investigation and control of the situation in the field of institutional occurrence.

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At the same time, under the International Health Regulations, cases were reported through the national call center to PAHO/WHO and a request for information was sent to the case’s home country on the pathogen history of the clinic where one of the patients was transferred to the hospital.

Candida auris is an emerging pathogen that was first isolated and described in 2009. In 2011, the first case of the blood fungus caused by this species was described, and in 2012 the first hospital outbreak was reported in the Americas region. Since the first case in 2009, Candida auris has been reported as the causative agent of invasive infections in humans in at least 47 countries. It is transmitted through contact with contaminated environments or with colonized people.



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